The Figure below illustrates a Clonal Proliferation Model of Cancer. This model might help you to make the leap from the detailed view we have had to the greater picture of cancer in a particular tissue.

Clonal proliferation of cancer

Hallmarks of Cancer - A monumental Review article about cancer written by experts in the field

Introduction to The Hallmarks of Cancer Series

The Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals

The Hallmarks of Cancer 2: Insensitivity to Antigrowth Signals

The Hallmarks of Cancer 3: Evading Apoptosis

The Hallmarks of Cancer 4: Limitless Replicative Potential

The Hallmarks of Cancer 5: Sustained Angiogenesis

The Hallmarks of Cancer 6: Tissue Invasion and Metastasis

The Hallmarks of Cancer 7: Genome Instability and Mutation

The Hallmarks of Cancer 8: Tumor Promoting Inflammation

The Hallmarks of Cancer 9: Reprogramming Energy Metabolism

Mapping the Cancer Genome - A Scientific American article

The Virus Behind the Cancer - Yale Medicine article about HPV, Henrietta Lacks, and Cancer